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Shahnaz Armin

Shahid Beheshti University of Medical Sciences, Iran

Title: Prediction severity of COVID-19 in hospitalized paediatrics

Biography

Biography: Shahnaz Armin

Abstract

Background: The novel severe acute respiratory syndrome-coronavirus-2 (SARS-COV-2) infection has appeared in China, in December 2019, then other countries all around the globe including Iran had encounters with this infection. Early symptoms of COVID-19 such as fever, sore throat, cough, illness, rhinorrhea, diarrhea, vomiting, stomach pain are analogous between children and adults. We have designed this study to prediction of severity in hospitalized children.

Method: This multi-central cross sectional study was carried out from March 2020 to October 2020, on 238 hospitalized confirmed COVID-19 paediatric cases in several major educational paediatric hospitals in 4 citys: Tehran, Ahwaz, Isfahan, and Bandar Abbas. Medical records about epidemiologic data, past medical history, underlying diseases, symptoms, para-clinical data and treatment information were all collected in standardized forms.

Results: 38% of all patients had at least one underlying disease. 41% of patients had a history of contact with suspected or confirmed cases and 11% had participated in gatherings. Among these hospitalized patients, 59% had pulmonary involvements and 12 cases (5%) were expired. In our study, the use of antibiotics and antivirals in hospitalized children with a diagnosis of COVID-19 is 82% and 39%, respectively and also, the most prevalent clinical symptoms were fever (73%),cough(39%),vomiting(29%),diarrhea(18%), and myalgia(13%).

Conclusion: Evaluation of SGOT, CRP, ALC, LDH, WBC, O2sat, Ferritin levels in children with COVID-19 can be an indication for hospitalization, and a predictor of disease severity, helping out clinicians in the management of patients.